Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p264 | (1) | WCRB2014

Placental phenotype of Turner mouse model: differences between XmO and XpO

Lim Shujing Jane , Ojarikre Andrew , Chuva de Sousa Lopes Susana M

Background: Turner syndrome in human arises from the loss of genetic material from a sex chromosome, resulting in the 45,XO genotype, with the remaining X chromosome being maternally-inherited (Xm) or paternally-inherited (Xp). As the gene dosage and expressions of Xp and Xm chromosomes are epigenetically different, this study aims to investigate the different influences of Xm and Xp on placental phenotype, using a mouse model.Methods: 14 placentas from ...